AlphaFold took the number of known protein structures from 190,000 to 200 million. I would expect that there will be whole new breakthroughs and industries created around that knowledge. And I can't wait to see what GPT-4 is, having experienced GPT 3.5 in the form of chat GPT. If the Lopener Prize was still running, and it appears to have stopped without any fanfare in 2019, that the text version of it would be one easily next year. But I think there will be some form of Turing test competition created, and that something based on chat GPT or similar will pass it.

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