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The Effects of CAR T on Respiratory Viral Infections
In the first 30 days after CAR T, rates of respiratory viral infections range between 8 and 20%. And those rates were significantly higher later on. The major predictor for viral infection was a low IgG level prior to the fluency. In terms of risk stratification, we do not have a specific or tangible tool to use yet. There certainly is a high risk for severe disease and higher mortality due to respiratory viral infections in these patients.