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Episode 17. Acquired Aplastic Anemia
Blood Cancer Talks
How to Differentiate Aplastic Anemia From Hypoplastic MDS
The presence of a P&H clone really distinguishes between inherited and acquired disease. True hypoplastic MDS though may not have as low of CD34 progenitors as aplastic anemia does, where usually in severe disease they're essentially unable to be found by flow cytometry. And then dysplasia, I never worry about dysplasia in the erythroid lineage in aplasticanemia because there can be stress erythropoecis that makes them look a little funny. But certainly if there's profound dyspoecis, really abnormal looking megacaryocytes, all kinds of neutrophilic dysplasia,. that's more in keeping with
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