Advancements in Precision Immunotherapy for Ankylosing Spondylitis

This chapter delves into the complexities of T-cell depletion in treating ankylosing spondylitis and introduces a bispecific antibody aimed at selectively targeting TRBV9 receptor-positive T cells. It also discusses the potential role of TRBV5 in uveitis, indicating a need for combined receptor blocking strategies and further research in human subjects.