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Joel Rurik: CAR-T Therapies to Reverse Cardiac Fibrosis

Talking Biotech with Dr. Kevin Folta

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Pibrosis - What Causes It?

Pibroses is the extra cellular matrix, or what i think of as the structural scaffolding of the heart. In disease there's a real shift from a healthy, dynamic, pliable ex cella matrix towards waiy too much. What we call fibrosis, is a real over abundance or accumulation and stiffening of the matrix. And it can have a lot of downstream effects. It's a common pathology across many organs and many diseases.

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