Is There a Drug to Overcome Compound Mutations After Latinib Resistance?

When you have the compound mutations after latinib there's nothing we have which really works. In iampower 150 feet spachytaxylencaboplatin what we know since a long time maybe 10 years that's the activity of pemetrach said in alkyl positive diseaseProbably due to the tyvelac sensitase which is overexpressed in an alkylpositive disease and as you can see here a nice pfs and response rate is related to kimo therapy. We still don't know today it might be another biology too  what do we have as drug to overcome compound mutations met after latiib resistance.