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Cell Therapies of the Future with Dan Goodman

Translation

CHAPTER

Is There Something About T Cell Exhaustion That Makes Cars Work?

There's something about CAR-T that makes cars work especially well. So, you have this costim library. You put them into a very standard CAR-T receptor architecture. And I'm sure we could talk for hours about how difficult and all of the things that went into actually putting that library together. But my favorite part of the paper is actually how much effort you gave the final T cell product as clinically relevant as possible.

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