Keynote by Prof. Sebastian Schneeweiss | The Effective Statistician Conference 2024

What You’ll Learn:

✔ The motivation behind emulating randomized trials using real-world data

✔ How claims and EHR data can support regulatory-grade evidence

✔ What makes a trial emulation good vs. suboptimal

✔ The role of adherence, measurement limitations, and data quality

✔ Use cases where RWE could expand indications or replace costly trials

✔ Key takeaways from the RCT DUPLICATE project and the “Benchmark-Calibrate-Extrapolate” strategy

Recommended For:

✔ Biostatisticians and epidemiologists

✔ Health tech innovators and data scientists

✔ Regulatory affairs and clinical development professionals

✔ Anyone involved in real-world data, RWE, or comparative effectiveness research

Resources & Links:

🔗 JAMA 2023 RCT DUPLICATE Publication

🔗 RCT DUPLICATE protocols and SAPs on ClinicalTrials.gov

🔗 FDA Framework for Real-World Evidence

🔗 The Effective Statistician Academy – I offer free and premium resources to help you become a more effective statistician.

🔗 Medical Data Leaders Community – Join my network of statisticians and data leaders to enhance your influencing skills.

🔗 My New Book: How to Be an Effective Statistician - Volume 1 – It’s packed with insights to help statisticians, data scientists, and quantitative professionals excel as leaders, collaborators, and change-makers in healthcare and medicine.

🔗 PSI (Statistical Community in Healthcare) – Access webinars, training, and networking opportunities.

If you’re working on evidence generation plans or preparing for joint clinical advice, this episode is packed with insights you don’t want to miss.

Join the Conversation:
Did you find this episode helpful? Share it with your colleagues and let me know your thoughts! Connect with me on LinkedIn and be part of the discussion.

Subscribe & Stay Updated:
Never miss an episode! Subscribe to The Effective Statistician on your favorite podcast platform and continue growing your influence as a statistician.

423 - Catholic Unscripted - Violence as the New Normal

The Symbolic World

Eucharist, Presence, and Social Meaning

The AI-powered Podcast Player