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iwCAR-T Session III: CAR-T therapy in AML: ongoing challenges and strategies to improve patient outcomes

VJHemOnc Podcast

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Introduction

The chapter explores the ongoing challenges faced in implementing CAR-T therapy in AML, including identifying suitable target antigens and addressing antigen heterogeneity. The potential of integrating CAR-T cells into an allogenic stem cell approach to reduce relapse after transplantation is also discussed, along with the importance of targeting leukemia stem cells to prevent relapse.

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