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What drives evolution? | Denis Noble | Reason with Science | Darwin | Selfish genes | Richard Dawkins

Reason with Science

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The Importance of Genomics in Understanding Major Diseases

The big outcome of genomics is not what was originally envisaged. We haven't arrived at a new understanding of major diseases except for the genetic outliers, such as cystic fibrosis. For those genomics has succeeded very much in identifying which genes are most strongly correlated with the disease state. But for the great majority, the correlation between the presence or absence of a gene and the presence or disappearance of a disease state is actually very low. That means that we cannot find the answer in genomics. I applaud the genomics groups for having discovered that, but we now need to do what is necessary.

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