Understanding Dementia: Types and Pathology

This chapter provides an in-depth analysis of the primary types of dementia syndromes, including Alzheimer's disease, vascular dementia, and dementia with Lewy bodies. It explores the symptoms, diagnostic challenges, and unique pathological features associated with these conditions, focusing on tau pathology and its implications. Additionally, the chapter highlights the connection between REM sleep behavior disorder and alpha-synucleinopathies, along with the role of amyloid precursor protein in Alzheimer’s neurodegeneration.