The Effect of IV Fluid Restrictions on Severe AKI

The Kaplan-Meyer curves were very similar in the two groups. We found that restrictive IV fluid did not impact the number of serious adverse reactions to IV crystalloids in the ICU. The distribution of days alive and out of hospital at day 90 in the two intervention group was also same. In conclusion we think that we in the classic trials successfully managed to recruit severely ill patients with septic shock and we had 99.4% follow up for our primary outcome. And this occurred despite that we do have some protocol violations in classic.