Uncovering Harmful Medical Treatments through Randomized Controlled Trials

This chapter explores two examples of medical treatments that were initially believed to be effective but were proven to be harmful through randomized controlled trials. The speakers discuss their surprise at the ineffectiveness of a procedure for treating cardiogenic shock and highlight the fallacy of assuming dire disease states eliminate the need for randomized studies. They also emphasize the importance of considering the applicability of clinical trial data to different patient populations.