Exploring Stem Cell Dynamics and Evolution

This chapter chronicles the speaker's transition from mouse models to human embryonic stem cell research, examining the ethical challenges and collaborative efforts involved. It highlights the significance of model organisms in uncovering insights into stem cell biology and the evolutionary conservation of mechanisms across species. The discussion also focuses on the intricacies of cardiovascular development, particularly the roles of TGF-beta signaling and the cytoskeletal protein Rudhira in blood lineage differentiation and angiogenesis.