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EP16 – NMJ & Suxamethonium | MiniPod | CT10

Count to 10 - Anaesthetic Primary Podcast

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Pharmacokinetics and Metabolism of Succinylcholine

This chapter explores the pharmacokinetics and metabolism of succinylcholine, detailing its absorption, distribution, breakdown, and unique metabolism outside the neuromuscular junction. It covers how succinylcholine is broken down into succinic acid and choline molecules, with a focus on plasma cholinesterase activity and its impact on succinylcholine metabolism. The chapter also touches on potential adverse effects of succinylcholine, including myalgia, muscle pain, apnea, and hypersensitivity.

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