#33 - Rudy Leibel, M.D.: Finding the obesity gene and discovering leptin
The Peter Attia Drive
00:00
How to Control Body Weight in Animals
The zucca rat stored an unbelievable amount of energy, but it was disproportionately taking those circulating metabolic fuels and putting them into storage. So that if you buy this idea that something is sensing energy availability, that would naturally ive the hyper phasia an correct. And the other model, the one more consistent, say, with the o b or the d b mouse, was the so called push model, which is that fat cells were being filled up because the brain itself had a a pushing, pushing the sub straight.
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