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Ep. 96: “Mentorship in Science” Featuring Dr. Nicole Quinn

The Immunology Podcast

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Aging, Immunity, and Cancer Adaptation

This chapter explores a recent study on brain aging and its immune implications, particularly focusing on microglia and macrophages. It discusses how aging leads to chronic inflammation in the brain and a shift in T-cell populations, as well as the impact of viral infections on this immune landscape. Additionally, the chapter investigates cancer cells' adaptive mechanisms to thrive under nutrient depletion, specifically through the emergence of neoepitopes that may enhance immunotherapy strategies.

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