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Ep. 24: “Autoimmune Disease” Featuring Dr. Jennifer Gommerman

The Immunology Podcast

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The T Car, Intrinsic Regulatory Potential

Only tecels that recognize self m h c to some extent and don't o highly recognize self antigens are allowed to e exit the thymus. So they focus on the different components off ofaof a t sar receptor, or a particular chain that has a variof, a v segment, a d segment, a j segment and a very highly variable c d r three region. And they use that to generaalgaritm that will predict whether the cell is more likely to be a te reg or a conventional tea cel.

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