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What's Carbon? And What Does Life Do?
NASA astrobiology is looking for more universal things that may not depend on carbon. But our search does tend to be focused on quote, life as we know it. We could talk about chemical disequilibrium life changing the chemical balance of its environment in a way that non-life probably doesn't. And if you go that route, it doesn't have to be carbon-based. It just has to be something that's multiplying itself and using energy.