Every kind of ignorance is natural. It's always been the case that i don't know spanish. If i want to change the situation, if i want to know spanish, i've to put in the effort to get that knowledge. So knowledge has to be now acquired, not something to be done, but something to be known. And here, the special object of this knowledge is not an object. That's the thing. The special object of the knowledge here, the subject is you, yourself. Knowledge is the name of the game here.
Swami Sarvapriyananda teaches the Katha Upanishad, which is one of the most popular Upanishads. The scripture concerns the story of a young man who goes to the house of death to find out what happens after death. The reply describes the nature of reality and the meaning of life.