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#459 DIGEST: Finerenone for Heart Failure, PCV21 and the latest Pneumonia Vaccine Recs, 24-hour vs 15-hour Oxygen Therapy, and PREVENT vs PCE for Cardiovascular Risk Estimation

The Curbsiders Internal Medicine Podcast

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Vaccine Innovations and Oxygen Therapy Trials

This chapter explores the effectiveness of polysaccharide vaccines, particularly the new PCV-21, and its implications for patient vaccination schedules, particularly for at-risk individuals. Additionally, it discusses a clinical trial investigating the effects of varying durations of supplemental oxygen therapy on patient outcomes, emphasizing the importance of study design and patient preferences. The conversation highlights both the challenges in navigating vaccination guidelines and the subtle intricacies of trial methodologies in clinical practice.

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