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Management Of Acute - On - Chronic Liver Failure: Part 1

Critical Matters

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The Role of Platelet and INR in Liver Disease

The new development or the better understanding now of a way to really assess this dynamic situation that you described in liver disease with either rotem or thrombolastography over using our usual parameters such as INR and platelet. You made a strong recommendation for using this type of testing and assessing the risk of bleeding and patients were undergoing procedures and surgery, correct? Yes. So that was based on one randomized controlled trial,. It was an open label randomized controlled trial of 60 patients in cirrhosis who were scheduled to undergo invasive procedure. And what really happened was that it resulted in many fewer patients being transfused.

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