Depressed Patients Have a Greater Activity of the Default Mode Network

An exploration of the role of the neurotransmitter serotonin in the development of depression. I discuss the role of serotonin in promoting the production of neurotrophic growth factor, the role the growth factor plays in facilitating neurogenesis and neural plasticity, and the various regions of the brain which are implicated in depression. I conclude by discussing the various cognitive distortions and other phenomena associated with depression, and how they can be treated by both pharmacotherapy and psychotherapy. Recommended pre-listening is Episode 38: Neurons and Synapses.

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