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TWiV 1211: Moo flu and dengue two

This Week in Virology

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Advancements in Dengue Vaccine Development

This chapter explores the complexities of antibody production in response to dengue virus, highlighting the challenges in previous vaccines and the importance of E-protein structure for effective immunization. It emphasizes the significance of collaborative research in enhancing the efficacy of vaccines through stabilizing mutations and optimizing antibody responses. Additionally, the discussion covers specific experiments that illustrate the intricate relationship between protein configuration and immune response, underscoring the critical balance needed in vaccine engineering.

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