Caucasians were amazing. We can stuff a whole boatload of fat into our bodies before we get types. And so there's some kind of threshold at which the adipose tissue says, no, Mass. I can't take any more and it stops listening to the signal. It becomes insulin resistant. There are multiple really interesting things that control this. You see this in people with different autoimmune conditions such as Schurgren's rheumatoid arthritis.

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