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Salmonella and Invasive Disease
Salmonella causes a lot of inflammation in your gut. So this is something that's totally different that these non typhoid oselmanelas do that typhoid doesn't do. And so one of the things that we have seen is that there are inherited deficiencies in certain inflammatory like systems, IL-12 and IL-23. People with deficiencies in these systems are at much higher risk of invasive non typhoidal salmonella infection. Being very young, under five, being very old, so over 70 or 75.