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Self Experiments In the Biochemically Unoptimized State

Mastering Nutrition

CHAPTER

The Effects of Alcohol on Lactate Levels

The only time I've ever seen my lactate at 4 millimoles per liter was after drinking a beer. The average human has almost 5 liters of blood, 3 liters of which is plasma. Ethanol is metabolized primarily in the cytosol of the liver where alcohol dehydrogenase uses NAD+. To oxidize it to acetaldehyde, loading electrons onto NAD+, forming NADH. Acetate is then joined to CoA to form acetyl CoA, and has the same fate as acetylCoA from any other source.

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