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Portal Hypertension and Colony Circulation
There's a lot of different causes and the actual site of the increased portal resistance depends on the etiology. This is actually defined as a hepatic vein pressure gradient, HVPG, greater than 6 millimeters of mercury. So if you have increased portal hypertension, this will result in portal systemic venous coladarols, acides, hepatic encephalopathy, splintomegaly.