This chapter explores the controversial withdrawal of U.S. funding for Gavi, the Vaccine Alliance, amidst rising anti-vaccine sentiments tied to the previous administration. It discusses concerns over new appointments to health advisory boards lacking credible expertise and the effects of misinformation on public confidence in vaccination. The chapter emphasizes the global repercussions of these developments, particularly in relation to vaccine safety, public health policies, and the tragic consequences seen in Samoa due to reduced vaccination rates.