AldoXS Causes Hyperglomerular Hyperfiltration

AldoXS causes hyperglomerular hyperfiltration, which is going to make their GFR look better than it truly is. So that there's probably some underlying kidney damage even more pronounced than what we suspect based on the lambs. If you send patients to adrenalctomy and cure their primary aldosteroneism, creatinine can go up significantly because a lot of those patients are completely inadequately treated until they get adrenalCTomy.