How Tolerance to Spiciness Develops

#048 Rebroadcast

New College-Style Sweatshirt!
And the Ghost Halloween Design is Back!

This week, Melissa and Jam dive into spiciness. What is it? Is it a flavor? Is it a feeling? Is it both? Is it more? Why can some people handle more than others? Does spiciness have any benefits?

References from this episode

1. https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/vanilloids
2. Solomon’s Organic Chemistry 11th edition
3. Analogues of Capsaicin with Agonist Activity as Novel Analgesic agents; Structure-Activity Studies 2. The Amide Bond “B-Reigion” byWalpole et. al
4. Similarities and Differences in the Structure−Activity Relationships of Capsaicin and Resiniferatoxin Analogues by Walpole et. al
5. Detailed Analysis of the Binding Mode of Vanilloids to Transient Receptor Potential Vanilloid Type I (TRPV1) by a Mutational and Computational Study by Ohbuchi et. al
6. The Art and Science of Organic andNatural Products Synthesis - by Nicolau et. al
7. https://www.acs.org/content/acs/en/pressroom/reactions/videos/2015/why-are-hot-peppers-hot-and-how-milk-helps.html

Find us on Instagram, Twitter, and Facebook @ChemForYourLife. Email us at chemforyourlife@gmail.com And check out our chill, simple little website at https://chemforyourlife.transistor.fm/

 

Thanks to our monthly supporters

• Scott B
• Jessie Reder
• Ciara Linville
• J0HNTR0Y
• Jeannette Napoleon
• Cullyn R
• Erica Bee
• Elizabeth P
• Sarah Moar
• Rachel Reina
• Letila
• Katrina Barnum-Huckins
• Suzanne Phillips
• Venus Rebholz
• Lyn Stubblefield
• Jacob Taber
• Brian Kimball
• Emerson Woodhall
• Kristina Gotfredsen
• Timothy Parker
• Steven Boyles
• Chris Skupien
• Chelsea B
• Bri McAllister
• Avishai Barnoy
• Hunter Reardon

★ Support this podcast on Patreon ★ ★ Buy Podcast Merch and Apparel ★

Check out our website at chemforyourlife.com

Watch our episodes on YouTube

Find us on Instagram, Twitter, and Facebook @ChemForYourLife

 

Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.