The History of the Aztecs

The Aztecs had never seen a European disease like that. They didn't quite understand infection as we know it today, but they did understand empirically how to treat it. And so they believe in quarantines and some rudimentary hygiene. That meant when a conquistador got smallpox, they would remove him from the other conquistadors. There's a lot of contemporary Aztec art where people have these horrific postules all over their body.