3min chapter

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#123 – Manolis Kellis: Origin of Life, Humans, Ideas, Suffering, and Happiness

Lex Fridman Podcast

CHAPTER

The Epigenome as a Musical Score

The epigenome allows you to effectively conduct the orchestra and sort of coordinate the pieces so that every instrument plays only the things that it needs to play. It's like having all of human knowledge in 23 volumes, like 23 giant books, which are your chromosomes. Every single cell has a different profession, a different role. And many genes are converging onto the function of one cell, and many cells are converging on the function ofone tissue or organ.

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