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Gene Therapy
The new approach is to actually go straight in the disease, sequence the genome of a thousand or so patients and find some correlation between mutations and the disease. This is actually a different branch of personalized medicine, which is preventive medicine. We can know that an individual has increased probability of showing the disease, exhibiting the disease. And we don't know how it happens or why it happens, but we have this marker that allows us to do this from now.