Dr. Chapa’s Clinical Pearls.  cover image

Syphilis' Vertical Transmission (Congenital Syphilis)

Dr. Chapa’s Clinical Pearls.

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The Implications of Maternal Diagnosis of Syphilis

The way that we prevent vertical transmission is early identification or early screening, early identification and appropriate treatment. Diagnosis of congenital syphilis can be super difficult because maternal non-trepinimal and the trepineemal IgG antibodies are transferred from the placenta to the baby so that complicates the interpretation of any reactive serological test. All babies born to mothers who have a positive confirmatory trepinemal test must be delivered with a quantitative non-t reprinimal serum test. umbilical cord blood can become contaminated with maternal blood and yield a false positive result.

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