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SGEM#468: Wide Open Monocytes – Using MDW to Diagnose Sepsis

The Skeptics Guide to Emergency Medicine

CHAPTER

Evaluating Monocyte Distribution Width for Sepsis Detection

This chapter explores the potential of monocyte distribution width (MDW) as a promising biomarker for early sepsis diagnosis, particularly in emergency settings. It critically analyzes diagnostic accuracy based on systematic reviews while addressing concerns about methodological quality and biases in relevant studies. Additionally, the chapter compares older and newer sepsis diagnostic criteria, emphasizing the complexities involved in interpreting the effectiveness of MDW.

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