SARS-CoV-2 Variants and the Central Nervous System

The chapter delves into a research paper on the impact of SARS-CoV-2 variants on the central nervous system, discussing potential direct infection of brain cells and resulting neurological deficits. It also explores the use of induced pluripotent stem cells in 3D organoid cultures to study cellular effects, along with challenges in replicating brain complexity. Additionally, the chapter analyzes the permissiveness of neural cells to SARS-CoV-2, focusing on viral replication and infectivity levels.