This chapter discusses a recently published paper in the journal epilepsy on the treatment of seizures in neonates, emphasizing the collaborative effort of a multidisciplinary team in bringing the paper together. It explores the systematic review of literature and the expert Delphi process used in the guideline, leading to important recommendations for neonatal seizure treatment. The chapter also addresses the approach to managing neonatal seizures, including medication use and neurodevelopmental outcomes.

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