How GLP-1s and tirzepatide work

Why does your body start “shape shifting” in midlife, even if you’re doing everything “right”? And what’s really behind all the GLP-1 buzz? Endocrinologist and weight-management specialist Dr. Beverly Tchang explains the science behind midlife metabolism, why BMI alone doesn’t tell the full story, what GLP-1s actually do in the body, and what women should know before considering these treatments.

Links to resources mentioned in this episode:

Dr. Beverly Tchang’s Professional Disclosures

SWAN Study (Study of Women’s Health Across the Nation)

HOMA-IR Calculator (for assessing insulin resistance)

STEP 1 Trial – Semaglutide for weight management

SURMOUNT-1 Trial – Tirzepatide for weight management

Note: In this show, we use “women” as shorthand for people with XX chromosomes. We understand sex and gender are more complex, and acknowledge the experiences we describe reach beyond that word.

See omnystudio.com/listener for privacy information.