Georgopoulos' direction-tuning and cosine model

Historically, the analysis of neural recordings focused on responses of single neurons recorded by single-contact electrodes. Modern electrodes with multiple electrode contacts can instead record spikes (action potentials) from hundreds of neurons simultaneously.

Manifold analysis of the overall population activity of these neurons has become a critical tool for interpretation of such data.

The podcast guest is a pioneer in the development and use of such analysis.