Navigating the Complexities of Predictive Biomarkers and Survival Endpoints
This chapter explores the intricacies of biomarker research, especially predictive biomarkers and survival endpoints. It emphasizes the challenges with current models like Cox regression and advocates for innovative approaches to improve prediction accuracy, incorporating insights from recent studies.
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Interview with Julia Geronimi and Pavel Mozgunov
Why You Should Listen:
✔ You’ll learn a new method that’s both statistically sound and easy to implement
✔ You’ll see how to pre-specify your analysis strategy for biomarker evaluation
✔ You’ll understand how to get more value out of small sample sizes
✔ And you’ll come away with a fresh appreciation for the complexity—and opportunity—in biomarker-based trials
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