Paxlovid and Long COVID: A Complex Discussion

In his weekly clinical update, Dr. Griffin and co-host Vincent Racaniello lament about the public changes from withdrawing from the WHO to health and scientific communication pauses by the Trump Administration after a brief discussion of Marburg in Tanzania and mpox in England before reviewing cats and bird flu, the recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, provides information for Columbia University Irving Medical Center’s long COVID treatment center, and where to go for answers to your long COVID questions.

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• Tanzania confirms Marburg virus outbreak (Reuters)
• Clade Ib mpox in England (Reuters)
• Withdrawing from the World Health Organization (WhiteHouse)
• Fees costs behind withdrawing from WHO ….is that what we are suppose to believe? (Sky News)
• Sorry to see you go, US? (WHO)
• Where are the updates? (CDC Health Alert Network)
• Pause in health communications of all kind (Washington Post)
• NIH chaos…..streaming to a halt? (STAT News)
• Devastation at the NIH, hiring traveling, meetings, communications(Science)
• Protect your cat from bird flu (NPR)
• No communication and cats with bird flu….does not sound good (CIDRAP)
• Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Weekly surveillance report: clift notes (CDC FluView)
• Baloxavir marboxil for prophylatix against influenza(NEJM)
• Comparative effectiveness of baloxavir marboxil and oseltamir treatment for reducint household transmission of influenza (Influenza and other respiratory viruses)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• COVID-19 national and regional trends (CDC)
• Host-microbe multiomic profiling identifies distinct COVD-19 immune dysregulation in solid organ transplant recipients (Nature Communications)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Where to get pemgarda (Pemgarda)
• EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Fusion center near you….if in NY (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Drug interaction checker (University of Liverpool)
• Real‐world effectiveness and safety of oral azvudine versus nirmatrelvir‒ritonavir (Paxlovid) in hospitalized patients with COVID-19 (Signal Transduction and Targeted Therapy)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
• Managing healthcare staffing shortages (CDC)
• Steroids, dexamethasone at the right time (OFID)
• Anticoagulation guidelines (hematology.org)
• Daniel Griffin’s evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID
• Long COVID Recovery Program with Zara Dureno, BA, MOT
• Letters read on TWiV 1186
• Dr. Griffin’s COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv