TWiV 1115: Calling the CoPs on flu
This Week in Virology
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Advancements in Self-amplifying RNA Vaccines and Efficacy of Fourth Booster Doses
The chapter delves into the development and potential advantages of self-amplifying RNA vaccines, with a focus on a specific COVID-19 vaccine that includes RNA replication machinery for prolonged expression and potentially lower doses. It also discusses a study comparing the efficacy and safety of a fourth booster dose using the Pfizer vaccine versus ARK154, noting a severe adverse event in the latter group. The chapter emphasizes the importance of enhancing immune responses with new vaccine technologies and effectively communicating their benefits to the public.
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