The HCM2 Iron Channel and Chronic Pain

The HCM2 iron channel is critical in triggering long-term pain. The channel can be driven by inflammatory mediators or possibly changes in the internal ambience of the nerve fiber, which switches on these channels as well. And one of the things that my lab's been trying to do is to develop blockers for this H CM2 iron channel,. So we're hoping to develop blockers, which could go into use as more effective pain killers with fewer side effects.