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Episode 267: RLR – Appetizer and Main Dish

The Clinical Problem Solvers

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Polyurea and Diabetes Mellitus?

Polyurea is actually defined as more than three liters a day in 24 hours. Polyurea has two causes: too much, there's too much solute and pure solvent. In this patient, the amount of hyperglycemia is way, way, way underwhelming compared to the amount of urine output they're having. So here we definitely, we know with a high degree of confidence that this patient has diabetes and cipitous. But he has three reasons for us to consider the possibility of central diabetes andcipitous. He also has hypothermalic pituitary abnormalities on his MRI.

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