Innovations in Musculoskeletal Health

This chapter explores the advancements in bioengineering and cell-based therapies targeting musculoskeletal disorders, particularly back pain. It highlights groundbreaking research into nucleus pulposus cells and the use of single-cell analysis and organ-on-a-chip models to understand pain mechanisms associated with intervertebral disc degeneration. The discussion emphasizes the importance of linking cellular interactions to patient-reported pain experiences, advocating for innovative methodologies to improve treatment outcomes.