2min chapter

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Healthspan, Lifespan, and the Biology of Aging

a16z Podcast

CHAPTER

Is There a Better Way to Prevent Aging?

We put it into various mouse models of muscle aging. We saw a positive impact in several different models, from sarcopenia to stem cell function to muscle atrophy. And we actually focused on the atrophy aspect for the clinic,. That's where we saw the biggest effect size in the shortest window of time. So that really motivated how we built the clinical trial. In fact, there was no significant difference in the muscle decline. so a really enormous effect size.

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