The Loss of Immuno Oncology Targets

I think that immuno oncology may be losing its luster. Would we expect it to keep coming up with new targets and Karen you may weigh in on this as well, or is this sort of an expectation that yeah there's just going to keep getting new and newer and newer targets all the time as a field grows? Well in cancer in general you keep seeing new targets emerging I mean, as we see there are 37 new ones at this conference that that I was able to find so I don't know if immuno Oncology is any different obviously these targets have sorts of different functions than some of the other types of things we're looking at for cancer. But one turn