Antibiotic Resistance, Space Launches and the Environment, Phage Therapy. May 5, 2023, Part 2
Science Friday
The Future of Phage Discovery
Dr. Graham Hatfield is a professor of biotechnology at the University of Pittsburgh in Pennsylvania. He says phages are very specific for an infection but could be genetically engineer to make them more broadly used as therapeutics. Dr. Hatfield: "I think that engineering and just doing the underlying genetics on some of these phages is going to provide some solutions"
SpaceX Explosion Damages Environment Around Launch Site
Last Thursday, SpaceX’s South Texas facility was awash in noise and fire, as crowds gathered in South Padre Island and Port Isabel to watch Starship’s first orbital launch.
It was the largest and most powerful rocket ever made, standing at around 400 feet tall. Four minutes into the launch, SpaceX detonated the rocket after the SuperHeavy booster failed to separate from the Starship as planned.
The launch destroyed the company’s launch pad, spreading concrete up to three quarters of a mile away. Cameras left by YouTubers were either knocked down or destroyed in the rumble, along with some of the fence surrounding the launch pad’s road-facing property.
To read the rest, visit sciencefriday.com.
The Private Space Race Takes A Toll On Planet Earth
After the SpaceX explosion last month, debris wasn’t the only thing on the minds of Science Friday listeners. The following messages arrived in our inbox after we reported on 3-D printed rockets in March.
It was interesting to hear you discuss 7 space launches in 5 days, and then just moments later the fact that we’re not on track to reduce carbon emissions. My understanding is that rocket launches release huge amounts of carbon and other greenhouse gases. Story idea?—@RevBobIerien, Twitter
Also regarding the 3-D rockets there wasn’t any concern made for space pollution was there? I may have tuned out unhappily before the end. —Juanita H, email
How much carbon do rockets contribute to global warming? —Robert C, email
Very disappointing to hear the report of new “cheaper” 3D-printed rockets are available so that, like fast food pods and big gulps, we can now drop even more cheap **** into the ocean. And, *immediately* following a story about the new report on climate change, what exactly is the carbon footprint resulting from the ability of more people to more cheaply fire rockets into space? —David M, email
Carbon isn’t the big pollutant that comes from spaceflight, says Dr. Eloise Marais, associate professor in physical geography at University College London. Instead, black carbon or soot particles are generated and released directly into the atmosphere, alongside reactive nitrogen and nitrogen oxides.
Dr. Marais joins Ira to talk about how much of an impact increased rocket launches could have on the atmosphere, and how that compares to the auto industry.
How To Combat The Antibiotic Resistance Crisis
For years scientists have been ringing alarm bells about a global antibiotic resistance crisis. Now hospitals and healthcare facilities face the consequences: In the United States, there are 2.8 million antimicrobial-resistant infections every year, and more than 35,000 people die from these infections.
Bacteria naturally try to outsmart the drugs designed to kill them, which causes treatments to become ineffective over time. While new antibiotics are made to respond to these resistant strains, the bacteria continue to evolve—creating a constant, and costly, cycle. There’s a number of added factors driving the crisis, including antibiotic use in livestock and the general overprescription of antibiotics. About 1 in 3 antibiotic prescriptions in outpatient settings like urgent care or emergency departments are unnecessary.
Scientists are struggling to keep up with the need to replace antibiotics that no longer work. It’s a never ending game of catch up.
Ira discusses some of the possible solutions to this vexing problem and takes listener questions with Dr. Victor Nizet, faculty lead of the Collaborative to Halt Antibiotic-Resistant Microbes at the University of California San Diego and Dr. Eddie Stenehjem, executive vice chair of medicine at the University of Colorado.
Are Phages A New Page In Medicine?
One of the many possible solutions to the global antibiotic resistance crisis is an old idea that’s new again—bacteriophages, or phages for short.
Phages are viruses that exist solely to kill bacteria and are abundant in nature.
While scientists first discovered phages’ ability to treat bacterial infections about a century ago, there’s been little interest in turning them into a treatment for patients with antibiotic resistant infections—until recently.
Ira talks with Dr. Graham Hatfull, professor of biotechnology at the University of Pittsburgh about the latest in phage science.
Transcripts for each segment will be available the week after the show airs on sciencefriday.com.
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