The Importance of Sleep in Predicting Mortality

In narcolepsy, there is this very strong association with a gene called HLA. And we discovered that there is an HLA subtype associated both with Alzheimer's, Parkinson's and ALS. It works through the creation of an autoimmune response against tau. So my hypothesis is that when you have this particular HLA, you develop an autoimmune disease against tau,. which actually reduces the probability of creating tau aggregates.